This article describes the experience when implementing social innovation concepts and methodologies in the development of business ideas and sustainable business initiatives in non-conventional organizations, in this specific case, an indigenous community. Although generating income is not one of the fundamental axes on which the activities of this type of organizations are based, incorporating design and innovation methodologies that are focused on human kind help individuals understand the personal and collective benefits that arise from the development of an entrepreneurial initiative, and motivate them to have a more active participation in the various activities leading to its implementation. Based on the double hexagon methodology, we carried out a process of accompaniment in which the work to achieve processes of self-organization and empowerment were performed by means of field visits and the active participation of community members. This document demonstrates that the principles that are associated with social innovation, as well as its methodologies, offer the possibility of accompanying business initiatives that respect the particular conditions of the community, so that this is the element that allows such initiatives to be incorporated as part of their culture, generating changes in people's habits, thus facilitating a successful implementation.
